Home»Tecnologie»E’ possibile predire l’epilessia?

E’ possibile predire l’epilessia?

0
Shares
Pinterest Google+

Una proteina sarà in grado di aiutare i medici a predire l’epilessia nelle persone a rischio, monitorarne l’evoluzione e l’eventuale insorgenza di forme resistenti alle terapie.

E’ ciò che ha rivelato uno studio pubblicato sul “Journal of Clinical Investigations”, condotto dagli scienziati dell’Irccs Istituto di ricerche farmacologiche Mario Negri di Milano, in collaborazione con i colleghi dell’università britannica di Liverpool.

La proteina si chiama HMGB1, ha proprietà infiammatorie ed è implicata nella generazione delle crisi epilettiche, viene indicata come “un potenziale biomarcatore predittivo della risposta terapeutica ai farmaci e dell’evoluzione della malattia in soggetti a rischio”.

I suoi livelli risultano infatti aumentati nel sangue dei pazienti con crisi epilettiche farmacoresistenti, rispetto a quelli che rispondono bene ai medicinali antiepilettici.

“Circa il 30% delle persone affette da epilessia ha crisi non controllate dai farmaci disponibili”, ricorda Annamaria Vezzani, coordinatrice del team di ricerca del Mario Negri, sottolineando che al momento “non esistono biomarcatori che possano predire lo sviluppo di epilessia in soggetti a rischio o la risposta terapeutica in pazienti alla prima diagnosi”. Il nuovo studio indica invece che “i livelli della proteina HMGB1 aumentano nel sangue prima che le crisi epilettiche si manifestino nei roditori, e possono dunque predire con accuratezza quali animali esposti a un fattore di rischio svilupperanno la malattia. In studi clinici paralleli, pazienti con nuova diagnosi di epilessia presentano un aumento della proteina nel sangue che è predittivo della comparsa di crisi farmacoresistenti”.

“La convalida di questi risultati, in studi clinici prospettici – aggiunge Vezzani – permetterà di sviluppare un nuovo biomarcatore coinvolto nella malattia da utilizzare sia per scopi terapeutici che prognostici”.

Fonte: Ansa

Previous post

Campagna "Controllati" per gli uomini italiani a partire dal 1 giugno

Next post

Quali benefici hanno gli animali da compagnia sui bambini?

73 Comments

  1. 05/10/2018 at 13:07

    I cling on to listening to the news talk about getting free online grant applications so I have been looking around for the most excellent site to get one. Could you tell me please, where could i find some?

  2. 05/10/2018 at 15:00

    I’m not that much of a online reader to be honest but your sites really nice, keep it up! I’ll go ahead and bookmark your site to come back down the road. Cheers

  3. 05/10/2018 at 15:07

    It’s a pity you don’t have a donate button! I’d definitely donate to this fantastic blog! I suppose for now i’ll settle for book-marking and adding your RSS feed to my Google account. I look forward to fresh updates and will talk about this blog with my Facebook group. Talk soon!

  4. 05/10/2018 at 19:24

    I do not even know how I ended up here, but I thought this post was good. I do not know who you are but definitely you’re going to a famous blogger if you aren’t already 😉 Cheers!

  5. 05/10/2018 at 21:24

    magnificent points altogether, you just gained a brand new reader. What would you suggest in regards to your post that you made some days ago? Any positive?

  6. 09/10/2018 at 12:27

    Valuable information. Lucky me I found your web site by accident, and I am shocked why this accident did not happened earlier! I bookmarked it.

  7. 09/10/2018 at 19:10

    I’m not that much of a internet reader to be honest but your blogs really nice, keep it up! I’ll go ahead and bookmark your site to come back later. All the best

  8. 10/10/2018 at 10:31

    Thanks for sharing superb informations. Your web-site is very cool. I’m impressed by the details that you have on this site. It reveals how nicely you perceive this subject. Bookmarked this website page, will come back for more articles. You, my pal, ROCK! I found simply the info I already searched everywhere and just couldn’t come across. What an ideal site.

  9. 10/10/2018 at 10:54

    Terrific work! This is the type of info that should be shared around the internet. Shame on Google for not positioning this post higher! Come on over and visit my website . Thanks =)

  10. 11/10/2018 at 0:35

    It’s the best time to make some plans for the future and it’s time to be happy. I have read this post and if I could I desire to suggest you some interesting things or tips. Perhaps you can write next articles referring to this article. I want to read even more things about it!

  11. 11/10/2018 at 20:28

    This actually answered my drawback, thanks!

  12. 12/10/2018 at 0:58

    I appreciate, cause I found exactly what I was looking for. You have ended my four day long hunt! God Bless you man. Have a nice day. Bye

  13. 12/10/2018 at 5:28

    Thanks for sharing excellent informations. Your web-site is very cool. I am impressed by the details that you’ve on this web site. It reveals how nicely you perceive this subject. Bookmarked this web page, will come back for extra articles. You, my friend, ROCK! I found simply the info I already searched everywhere and just couldn’t come across. What a great web-site.

  14. 13/10/2018 at 1:12

    Good write-up, I’m regular visitor of one’s blog, maintain up the nice operate, and It is going to be a regular visitor for a long time.

  15. 13/10/2018 at 20:03

    Oh my goodness! a fantastic article dude. Appreciate it However My business is experiencing problem with ur rss . Do not know why Not able to subscribe to it. Can there be everyone finding identical rss problem? Anybody who knows kindly respond. Thnkx

  16. 14/10/2018 at 14:19

    naturally like your web-site but you need to check the spelling on several of your posts. Several of them are rife with spelling problems and I find it very bothersome to inform the reality however I will definitely come again again.

  17. 15/10/2018 at 10:44

    Hey there! Do you use Twitter? I’d like to follow you if that would be ok. I’m undoubtedly enjoying your blog and look forward to new updates.

  18. 18/10/2018 at 13:45

    Hi, i think that i saw you visited my site so i came to “return the favor”.I’m trying to find things to enhance my web site!I suppose its ok to use a few of your ideas!!

  19. 19/10/2018 at 14:05

    Nice read, I just passed this onto a colleague who was doing some research on that. And he actually bought me lunch as I found it for him smile Therefore let me rephrase that: Thanks for lunch!

  20. 20/10/2018 at 14:00

    Hey I am so happy I found your blog, I really found you by error, while I was searching on Askjeeve for something else, Anyhow I am here now and would just like to say thank you for a tremendous post and a all round enjoyable blog (I also love the theme/design), I don’t have time to read through it all at the moment but I have saved it and also included your RSS feeds, so when I have time I will be back to read much more, Please do keep up the great work.

  21. 20/10/2018 at 17:47

    There are those who engage in this type of trading without sufficient knowledge; however, there are day traders who make a successful living despite, or perhaps because of, the risks.

  22. 20/10/2018 at 21:36

    Have you ever thought about creating an e-book or guest authoring on other websites? I have a blog centered on the same information you discuss and would love to have you share some stories/information. I know my viewers would value your work. If you’re even remotely interested, feel free to send me an e-mail.

  23. 21/10/2018 at 9:56

    [url=http://doxycycline-cheapbuy.site/]doxycycline-cheapbuy.site.ankor[/url] onlinebuycytotec.site.ankor

  24. 21/10/2018 at 10:31

    [url=http://doxycycline-cheapbuy.site/]doxycycline-cheapbuy.site.ankor[/url] onlinebuycytotec.site.ankor

  25. 21/10/2018 at 12:33

    Spot on with this write-up, I truly think this website needs way more consideration. I’ll probably be once more to learn way more, thanks for that info.

  26. 24/10/2018 at 11:30

    I have been reading out a few of your posts and i can state pretty good stuff. I will definitely bookmark your blog.

  27. 07/11/2018 at 9:31

    We absolutely love your blog and find many of your post’s to be what precisely I’m looking for. can you offer guest writers to write content to suit your needs? I wouldn’t mind producing a post or elaborating on a few of the subjects you write regarding here. Again, awesome web site!

  28. Rubin Kazan and CSKA Moscow have joined the list of clubs keen on Manchester City striker John Guidetti. The 20-year-old Swede has only ever played one game for City. Rubin Kazan and CSKA join the list of clubs after City’s Guidetti

  29. 11/11/2018 at 6:34

    Some filters use multiple filtration method.

  30. 11/11/2018 at 8:15

    Heya i’m for the first time here. I came across this board and I find It really helpful & it helped me out a lot. I hope to provide one thing again and aid others like you aided me.

  31. 13/11/2018 at 8:38

    I was suggested this website by my cousin. I’m not sure whether this post is written by him as nobody else know such detailed about my difficulty. You are amazing! Thanks!

  32. 16/11/2018 at 11:40

    Immigration Solicitors… […]below you’ll find the link to some sites that we think you should visit[…]…

  33. 17/11/2018 at 8:55

    hello!,I really like your writing so a lot! proportion we communicate more approximately your post on AOL? I require an expert in this house to resolve my problem. May be that is you! Taking a look ahead to look you.

  34. 17/11/2018 at 9:53

    This is the correct weblog for anybody who needs to seek out out about this topic. You realize a lot its nearly onerous to argue with you (not that I truly would need…HaHa). You positively put a brand new spin on a topic thats been written about for years. Great stuff, just nice!

  35. 17/11/2018 at 13:36

    You really make it appear so easy with your presentation but I to find this matter to be actually one thing which I think I’d by no means understand. It seems too complex and extremely wide for me. I’m looking ahead on your next post, I’ll try to get the cling of it!

  36. 17/11/2018 at 16:58

    Wow, incredible blog layout! How long have you been blogging for? you made blogging look easy. The overall look of your web site is excellent, let alone the content!

  37. 17/11/2018 at 17:28

    Pretty component to content. I just stumbled upon your weblog and in accession capital to claim that I acquire actually enjoyed account your weblog posts. Any way I will be subscribing for your augment and even I fulfillment you get admission to persistently rapidly.

  38. 18/11/2018 at 13:37

    This website can be a stroll-by for all the information you wished about this and didn’t know who to ask. Glimpse here, and also you’ll undoubtedly discover it.

  39. 18/11/2018 at 17:17

    Its like you read my thoughts! You appear to grasp a lot approximately this, such as you wrote the ebook in it or something. I feel that you just could do with some percent to drive the message home a bit, however instead of that, that is excellent blog. A great read. I will definitely be back.

  40. 19/11/2018 at 2:10

    Hello, i think that i saw you visited my weblog so i came to “return the favor”.I am trying to find things to enhance my web site!I suppose its ok to use a few of your ideas!!

  41. 19/11/2018 at 5:20

    Hey there! I’ve been reading your web site for a while now and finally got the bravery to go ahead and give you a shout out from Atascocita Tx! Just wanted to tell you keep up the good job!

  42. 19/11/2018 at 7:17

    Outstanding post however , I was wondering if you could write a litte more on this subject? I’d be very thankful if you could elaborate a little bit further. Cheers!

  43. 21/11/2018 at 7:18

    Every weekend i used to pay a quick visit this website, because i want enjoyment, as this this website conations truly good funny information too.

  44. 25/11/2018 at 20:41

    This does interest me

  45. 27/11/2018 at 22:21

    I love what you guys are up too. This sort of clever work and exposure!Keeep up the very ood woorks guys I’ve added youguys to blogroll.

  46. 30/11/2018 at 3:04

    I like the valuable info you supply to your articles. I’ll bookmark your weblog and take a look at again right here frequently. I’m moderately certain I’ll be told plenty of new stuff right here! Good luck for the following!

  47. 30/11/2018 at 18:51

    I delight in, cause I discovered exactly what I used to be having a look for. You have ended my four day long hunt! God Bless you man. Have a nice day. Bye

  48. 01/12/2018 at 1:39

    Yes, even with everything listing down, you continue to need to sit and compose acomplete response, exactly the same you’d probably write any essay.Cross out any irrelevant ones and earn your verybest self to set them into a logical order. If yousay because over and over again, the only thing the variousreaders is going to be alert to happens because – it’ll stifle your argument and it’salso at the top of their email list of items you shouldavoid within your academic work.

  49. 03/12/2018 at 0:47

    Heya i am for the first time here. I found this board and I find It really useful & it helped me out a lot. I hope to give something back and help others like you aided me.

  50. 04/12/2018 at 2:47

    I used to be recommended this web site by way of my cousin. I’m now not positive whether this publish is written through him as no one else understand such specific approximately my difficulty. You’re incredible! Thank you!

  51. 05/12/2018 at 1:46

    That is the correct weblog for anyone who desires to find out about this topic. You understand a lot its virtually arduous to argue with you (not that I really would want…HaHa). You positively put a new spin on a topic thats been written about for years. Great stuff, simply great!

  52. 06/12/2018 at 3:27

    No conversations open for The Battle Pussy-cats right now.

  53. 06/12/2018 at 5:37

    I was curious if you ever thought of changing the page layout of your website? Its very well written; I love what youve got to say. But maybe you could a little more in the way of content so people could connect with it better. Youve got an awful lot of text for only having one or 2 images. Maybe you could space it out better?

  54. 10/12/2018 at 14:46

    In your post it states that the Led light strips with tape on can still be used once Cut. I cut 1 inch off and tryed to find wires in it. Could nit find any at all as how could I use this long led strip or is it no good?

  55. 12/12/2018 at 2:50

    Appreciating the time and effort you put into your website and in depth information you provide. It’s nice to come across a blog every once in a while that isn’t the same out of date rehashed material. Great read! I’ve bookmarked your site and I’m including your RSS feeds to my Google account.

  56. 14/12/2018 at 0:15

    I’m extremely impressed along with your writing abilities as neatly as with the layout for your weblog. Is this a paid topic or did you customize it yourself? Either way keep up the excellent high quality writing, it’s rare to peer a great weblog like this one nowadays..

  57. Very neat blog post.Thanks Again. Much obliged.

  58. 18/12/2018 at 2:08

    Good day very nice website!! Man .. Excellent .. Superb .. I’ll bookmark your site and take the feeds also…I am happy to search out a lot of helpful info here within the put up, we want work out extra strategies in this regard, thanks for sharing. . . . . .

  59. 19/12/2018 at 14:23

    Greetings! Quick question that’s completely off topic. Do you know how to make your site mobile friendly? My blog looks weird when viewing from my iphone. I’m trying to find a theme or plugin that might be able to resolve this problem. If you have any suggestions, please share. Appreciate it!

  60. 19/12/2018 at 17:27

    Hi, Neat post. There’s a problem with your web site in internet explorer, would test this… IE still is the market leader and a huge portion of people will miss your wonderful writing because of this problem.

  61. 22/12/2018 at 3:29

    hello there and thank you for your information – I’ve certainly picked up anything new from right here. I did however expertise several technical issues using this web site, since I experienced to reload the web site a lot of times previous to I could get it to load properly. I had been wondering if your hosting is OK? Not that I am complaining, but slow loading instances times will sometimes affect your placement in google and can damage your quality score if advertising and marketing with Adwords. Well I’m adding this RSS to my email and could look out for much more of your respective interesting content. Make sure you update this again very soon..

  62. 23/12/2018 at 19:10

    My brother recommended I might like this blog. He was totally right. This post actually made my day. You can not imagine just how much time I had spent for this information! Thanks!

  63. Hello! Would you mind if I share your blog with my twitter group? There’s a lot of folks that I think would really enjoy your content. Please let me know. Cheers

  64. You can certainly see your enthusiasm in the paintings you write. The sector hopes for even more passionate writers such as you who aren’t afraid to mention how they believe. All the time follow your heart.

  65. It is perfect time to make some plans for the longer term and it’s time to be happy. I have read this submit and if I may just I want to recommend you few interesting issues or advice. Maybe you could write next articles relating to this article. I want to learn even more things about it!

  66. 26/12/2018 at 10:11

    The following time I learn a blog, I hope that it doesnt disappoint me as much as this one. I mean, I do know it was my option to learn, but I really thought youd have one thing interesting to say. All I hear is a bunch of whining about one thing that you could possibly fix for those who werent too busy looking for attention.

  67. 06/01/2019 at 23:23

    It’s laborious to seek out knowledgeable folks on this topic, but you sound like you recognize what you’re speaking about! Thanks

  68. I used to be recommended this website by my cousin. I am no longer sure whether this publish is written via him as no one else recognize such certain about my problem. You are amazing! Thank you!

  69. 11/01/2019 at 20:22

    It’s really a cool and useful piece of information. I’m glad that you shared this helpful information with us. Please keep us up to date like this. Thanks for sharing.

  70. 13/01/2019 at 1:00

    Hey there! Do you know if they make any plugins to assist with SEO? I’m trying to get my blog to rank for some targeted keywords but I’m not seeing very good results. If you know of any please share. Many thanks!

  71. 14/01/2019 at 18:13

    I and my friends were found to be reading through the best items from your web blog while then came up with an awful feeling I never thanked the web site owner for those tips. All the men had been for this reason happy to see them and have in effect without a doubt been using them. Appreciation for being so accommodating and then for settling on this kind of smart resources most people are really desperate to be aware of. My very own honest regret for not saying thanks to you sooner.

  72. 16/01/2019 at 20:46

    When I initially commented I clicked the “Notify me when new comments are added” checkbox and now each time a comment is added I get several emails with the same comment. Is there any way you can remove people from that service? Thanks!

  73. 18/01/2019 at 20:48

    Hi! Do you know if they make any plugins to help with Search Engine Optimization? I’m trying to get my blog to rank for some targeted keywords but I’m not seeing very good gains. If you know of any please share. Cheers!

Leave a reply

Il tuo indirizzo email non sarà pubblicato.